Invitrogen™ Fumarase Monoclonal Antibody (3D5A3G7)

Catalog No.	Quantity
PIMA529275	100 μL

Catalog No. PIMA529275 Supplier Invitrogen™ Supplier No. MA529275

Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Fumarate Hydratase/FH.

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Specifications

• Antigen: Fumarase
• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 3D5A3G7
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: FH
• Gene Accession No.: P07954
• Gene Alias: EF-3; Fh; Fh1; Fh-1; FMRD; fumarase; fumarate hydratase; fumarate hydratase 1; fumarate hydratase, mitochondrial; HLRCC; LRCC; MCL; MCUL1
• Gene Symbols: FH
• Host Species: Mouse
• Immunogen: Recombinant Human Fumarate Hydratase/FH protein (Ala45-Lys510).
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2271
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1