Invitrogen™ Fumarase Monoclonal Antibody (OTI1F10)

Catalog No.	Quantity
PIMA524989	100 μL

Catalog No. PIMA524989 Supplier Invitrogen™ Supplier No. MA524989

Description

Mouse Monoclonal Antibody

Fumarase Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Specifications

• Antigen: Fumarase
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: OTI1F10
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: FH
• Gene Accession No.: P07954, P14408, P97807
• Gene Alias: EF-3; Fh; Fh1; Fh-1; FMRD; fumarase; fumarate hydratase; fumarate hydratase 1; fumarate hydratase, mitochondrial; HLRCC; LRCC; MCL; MCUL1
• Gene Symbols: FH, Fh1
• Host Species: Mouse
• Immunogen: Full length human recombinant protein of FH produced in HEK293T cell.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14193, 14194, 2271, 24368, 480092
• Target Species: Human, Mouse, Rat, Canine
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1