Invitrogen™ Fumarase Monoclonal Antibody (OTI1F10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524989

Catalog No. PIMA524989

Description

Fumarase Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Specifications

• Antigen: Fumarase
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P07954, P14408, P97807
• Gene Symbols: FH, Fh1
• Immunogen: Full length human recombinant protein of FH produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: OTI1F10
• Conjugate: Unconjugated
• Gene: FH
• Gene Alias: EF-3; Fh; Fh1; Fh-1; FMRD; fumarase; fumarate hydratase; fumarate hydratase 1; fumarate hydratase, mitochondrial; HLRCC; LRCC; MCL; MCUL1
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14193, 14194, 2271, 24368, 480092
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid