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Invitrogen™ Fumarase Polyclonal Antibody
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Catalog No. PIPA522091
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100 μL
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Catalog No. Quantity
PIPA522091 100 μL
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Catalog No. PIPA522091 Supplier Invitrogen™ Supplier No. PA522091
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, mosue liver, rat liver. Predicted reactivity: Rat (96%), Zebrafish (86%), Pig (97%), Chicken (89%), Sheep (97%), Chimpanzee (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Fumarase
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene FH
Gene Accession No. P07954, P14408, P97807
Gene Alias EF-3; Fh; Fh1; Fh-1; FMRD; fumarase; fumarate hydratase; fumarate hydratase 1; fumarate hydratase, mitochondrial; HLRCC; LRCC; MCL; MCUL1
Gene Symbols FH, Fh1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Fumarate hydratase. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14193, 14194, 2271, 24368
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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