Invitrogen™ Fumarase Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5119129	Invitrogen™ PA5119129	200 μL
PIPA5121992	Invitrogen™ PA5121992	20 μL

Description

Fumarase Polyclonal Antibody for Western Blot, IHC (P)

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Specifications

• Antigen: Fumarase
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse, Rat
• Gene: FH
• Gene Alias: EF-3; Fh; Fh1; Fh-1; FMRD; fumarase; fumarate hydratase; fumarate hydratase 1; fumarate hydratase, mitochondrial; HLRCC; LRCC; MCL; MCUL1
• Gene Symbols: FH, Fh1
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography, Protein A

• Concentration: 0.88 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: P07954, P14408, P97807
• Gene ID (Entrez): 14193, 14194, 2271, 24368
• Immunogen: Recombinant protein Fumarase. The antigen corresponds to amino acid range 42-185 of the target protein.
• Product Type: Antibody