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Invitrogen™ FVT1 Monoclonal Antibody (2B2-3C11)
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Catalog No. PIMA518923
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100 μg
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Catalog No. Quantity
PIMA518923 100 μg
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Catalog No. PIMA518923 Supplier Invitrogen™ Supplier No. MA518923
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Description

Mouse Monoclonal Antibody

Peptide Sequence: FVLLLYMVSP LISPKPLALP GAHVVVTGGS SGIGKCIAIE CYKQGAFITL VARNEDKLLQ AKKEIEMHSI NDKQVVLCIS VDVSQDYNQV ENVIKQAQEK LGPVDMLVNC AGMAVSGKFE DLEVSTFERL MSINYLGSVY PSRAVITTMK ERRVGRIVFV SSQAGQLGLF GFTAYSASKF AIRGLAEALQ MEVKPYNVYI TVAYPPDTDT PGFAEENRTK PLETRLISET TSVCKPEQVA KQIVKDAIQG NFNSSLGSDG YMLSALTCGM APVTSITEGL QQVVTMGLFR TIALFYLGSF DSIVRRCMMQ REKSENADKT A.

The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FVT1
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2B2-3C11
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Kdsr
Gene Accession No. Q06136
Gene Alias 3-dehydrosphinganine reductase; 3-ketodihydrosphingosine reductase; 3-ketodihydrosphingosine reductase; LOW QUALITY PROTEIN: 3-ketodihydrosphingosine reductase; 6330410P18Rik; 9430079B08Rik; DHSR; follicular lymphoma variant translocation 1; follicular variant translocation protein 1; Follicular variant translocation protein 1 homolog; FVT1; FVT-1; KDS reductase; kdsr; MGC137214 protein; SDR35C1; Short chain dehydrogenase/reductase family 35C member 1; short chain dehydrogenase/reductase family 35C, member 1; unm_muz106; zgc:55947
Gene Symbols Kdsr
Host Species Mouse
Immunogen KDSR (AAH08797.1, 12 a.a. ~ 332 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2531
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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