Invitrogen™ FXR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529853

Catalog No. PIPA529853

Description

Recommended positive controls: HeLa, HepG2, mouse liver. Predicted reactivity: Mouse (99%), Rat (89%), Zebrafish (82%), Xenopus laevis (91%), Chicken (86%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. It may regulate intracellular transport and local transltion of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. FXR1 is required for embryonic and postnatal development of muscle tissue. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: FXR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fxr1
• Gene Alias: 1110050J02Rik; 9530073J07Rik; AI851072; FMR1 autosomal homolog 1; fragile X mental retardation autosomal homolog variant p1K; fragile X mental retardation autosomal homolog variant p2K; fragile X mental retardation autosomal homolog variant p4K; fragile X mental retardation autosomal homolog variant p5FK; fragile X mental retardation gene 1, autosomal homolog; fragile X mental retardation gene, autosomal homolog; fragile X mental retardation syndrome-related protein 1; fragile X mental retardation, autosomal homolog 1; fragile X mental retardation-related protein 1; fragile-X-related protein 1; Fxr1; Fxr1h; Fxr1p; hFXR1p; hypothetical protein LOC536793; mFxr1p
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14359, 361927, 8087
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.03 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P51114, Q5XI81, Q61584
• Gene Symbols: Fxr1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human FXR1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov