Invitrogen™ FXYD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104165

Catalog No. PIPA5104165

Description

Antibody detects endogenous levels of total FXYD2.

The human FXYD2 (pronounced fix-id) gene maps to chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA). FXYD2 gamma subunit modulates NKA activity by inducing ion channel activity. The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing 7 invariant and 6 conserved amino acids. Other members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD3 (Mat8, mammary tumor protein 8), FXYD4 (CHIF) and FXYD5 (RIC).

Specifications

• Antigen: FXYD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fxyd2
• Gene Alias: ATP1C; Atp1g1; ATPase, Na+/K+ transporting, gamma 1 polypeptide; FXTD domain-containing ion transport regulator 2; FXYD domain containing ion transport regulator 2; FXYD domain-containing ion transport regulator 2; FXYD2; gamma subunit of sodium potassium ATPase; GNAKATP; HOMG2; Na(+)/K(+) ATPase subunit gamma; regulator 2; Sodium Potassium ATPase; sodium pump gamma chain; sodium/potassium-transporting ATPase gamma chain; sodium/potassium-transporting ATPase subunit gamma
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11936, 486
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P54710, Q04646
• Gene Symbols: Fxyd2
• Immunogen: A synthesized peptide derived from human FXYD2(Accession P54710), corresponding to amino acid residues I32-P66.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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