Invitrogen™ FXYD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566670

Catalog No. PIPA566670

Description

Immunogen sequence: MTGLSMDGGGS PKGDVDPFYY DYE Highest antigen sequence identity to the following orthologs - mouse 46%, rat 63%.

The human FXYD2 (pronounced fix-id) gene maps to chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA). FXYD2 gamma subunit modulates NKA activity by inducing ion channel activity. The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing 7 invariant and 6 conserved amino acids. Other members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD3 (Mat8, mammary tumor protein 8), FXYD4 (CHIF) and FXYD5 (RIC).

Specifications

• Antigen: FXYD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fxyd2
• Gene Alias: ATP1C; Atp1g1; ATPase, Na+/K+ transporting, gamma 1 polypeptide; FXTD domain-containing ion transport regulator 2; FXYD domain containing ion transport regulator 2; FXYD domain-containing ion transport regulator 2; FXYD2; gamma subunit of sodium potassium ATPase; GNAKATP; HOMG2; Na(+)/K(+) ATPase subunit gamma; regulator 2; Sodium Potassium ATPase; sodium pump gamma chain; sodium/potassium-transporting ATPase gamma chain; sodium/potassium-transporting ATPase subunit gamma
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 486
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P54710
• Gene Symbols: Fxyd2
• Immunogen: Recombinant Human FXYD2. Recombinant protein control fragment (Product #RP-107318).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG