Invitrogen™ FZD10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575325

Catalog No. PIPA575325

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

FZD10/Frizzled-10 is a 581 amino acid protein belonging to the G-protein coupled receptor Fz/Smo family and containing a signal peptide, a cysteine-rich domain in the N-terminal, seven transmembrane domains and a C-terminal PDZ domain-binding motif. It is involved in transduction, intercellular transmission of polarity information during tissue morphogenesis in differentiated tissues and as a receptor for Wnt proteins. FZD10 is expressed highly in placenta, fetal kidney, fetal lung, brain cerebellum, cerebral cortex, medulla and spinal cord with very low levels in total brain, frontal lobe, temporal lobe, putamen, adult brain, heart, lung and skeletal muscle.

Specifications

• Antigen: FZD10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FZD10
• Gene Alias: CD350; CD350 antigen; frizzled 10, seven transmembrane spanning receptor; frizzled class receptor 10; frizzled family receptor 10; frizzled homolog 10; frizzled homolog 10 (Drosophila); frizzled homolog 10, pseudogene 1; frizzled-10; Fz10; Fz-10; Fzd10; Fzd10-ps1; FzE7; hFz10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11211, 363913, 93897
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8BKG4, Q9ULW2
• Gene Symbols: FZD10
• Immunogen: Synthetic peptide corresponding to amino acids 132-180 of Human FZD10.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG