Invitrogen™ FZD4 Monoclonal Antibody (2F3A7)

Catalog No.	Quantity
FERMA548644	100 μg

Catalog No. FERMA548644 Supplier Invitrogen™ Supplier No. MA548644

Description

Mouse Monoclonal Antibody

FZD4 Monoclonal Antibody for Western Blot, Flow, ELISA

FZD4 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Frizzled 4 is widely expressed, particularly in heart, skeletal muscle, ovary, and fetal kidney. Transcripts have also been identified in liver, kidney, pancreas, spleen, and fetal lung, and in smaller amounts in placenta, adult lung, prostate, testis, colon, and fetal brain.

Specifications

• Antigen: FZD4
• Applications: ELISA, Flow Cytometry, Western Blot, Western Blot
• Classification: Monoclonal
• Clone: 2F3A7
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% sodium azide
• Gene: FZD4
• Gene Accession No.: Q9ULV1
• Gene Alias: CD344; CD344 antigen; EVR1; FEVR; frizzled 4, seven transmembrane spanning receptor; frizzled class receptor 4; frizzled family receptor 4; frizzled homolog 4; frizzled homolog 4 (Drosophila); frizzled receptor 4; frizzled-4; Fz4; Fz-4; Fzd4; FZD4S; FzE4; GPCR; hFz4; mFz4; MGC34390; rFz4; WNT receptor frizzled-4
• Gene Symbols: FZD4
• Host Species: Mouse
• Immunogen: Purified recombinant fragment of human CD344 (AA: extra 37-222) expressed in E. Coli.
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8322
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1