Invitrogen™ FZD4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533555

Catalog No. PIPA533555

Description

Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Rat, Dolphin, Hamster, Elephant, Panda, Dog, Bovine (100%).

FZD4 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Frizzled 4 is widely expressed, particularly in heart, skeletal muscle, ovary, and fetal kidney. Transcripts have also been identified in liver, kidney, pancreas, spleen, and fetal lung, and in smaller amounts in placenta, adult lung, prostate, testis, colon, and fetal brain.

Specifications

• Antigen: FZD4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FZD4
• Gene Alias: CD344; CD344 antigen; EVR1; FEVR; frizzled 4, seven transmembrane spanning receptor; frizzled class receptor 4; frizzled family receptor 4; frizzled homolog 4; frizzled homolog 4 (Drosophila); frizzled receptor 4; frizzled-4; Fz4; Fz-4; Fzd4; FZD4S; FzE4; GPCR; hFz4; mFz4; MGC34390; rFz4; WNT receptor frizzled-4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100756296, 445416, 485149, 64558, 8322
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.4 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9QZH0, Q9ULV1
• Gene Symbols: FZD4
• Immunogen: Synthetic 18 amino acid peptide from N-terminal extracellular domain of human FZD4 / Frizzled 4.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat, Canine, Monkey, Bovine, Hamster
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov