Invitrogen™ FZD7 Polyclonal Antibody

Catalog No.	Quantity
PIPA547232	100 μg

Catalog No. PIPA547232 Supplier Invitrogen™ Supplier No. PA547232

Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 15% cross-reactivity with recombinant mouse (rm) Frizzled-2 and less than 5% cross-reactivity with rmFrizzled-3, rmFrizzled-4, rhFrizzled-5, rmFrizzled-6, rmFrizzled-8, and rmFrizzled-9 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Specifications

• Antigen: FZD7
• Applications: Immunohistochemistry (Frozen), Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: FZD7
• Gene Accession No.: Q61090
• Gene Alias: frizzled 7, seven transmembrane spanning receptor; frizzled class receptor 7; frizzled family receptor 7; frizzled homolog 7; frizzled homolog 7 (Drosophila); Frizzled, drosophila, homolog of, 7; frizzled-7; Fz7; Fz-7; FZD7; FzE3; hFz7; LOC100360552; mFz7; rCG22430-like; rizzled 7
• Gene Symbols: FZD7
• Host Species: Goat
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Frizzled-7 Gln33-Leu185.
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14369
• Target Species: Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG