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Invitrogen™ FZD8 Polyclonal Antibody
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Catalog No. PIPA518456
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100 μg
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Catalog No. Quantity
PIPA518456 100 μg
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Catalog No. PIPA518456 Supplier Invitrogen™ Supplier No. PA518456
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FZD8
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Fzd8
Gene Accession No. Q9H461
Gene Alias frizzled 8, seven transmembrane spanning receptor; frizzled class receptor 8; frizzled family receptor 8; frizzled homolog 8; frizzled homolog 8 (Drosophila); frizzled-8; Fz8; Fz-8; Fzd8; hFZ8; HGNC:4046
Gene Symbols Fzd8
Host Species Goat
Immunogen Synthetic peptide sequence (SYPKQMPLSQV) corresponding to the C-terminus amino acids of FZD8 (aa 684-694).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8325
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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