Invitrogen™ FZD8 Recombinant Rabbit Monoclonal Antibody (JB40-16)

Catalog No.	Quantity
PIMA534703	100 μL

Catalog No. PIMA534703 Supplier Invitrogen™ Supplier No. MA534703

Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Mouse lung tissue lysates, Human kidney tissue, human uterus tissue.

Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

Specifications

• Antigen: FZD8
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Recombinant Monoclonal
• Clone: JB40-16
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: Fzd8
• Gene Accession No.: Q9H461
• Gene Alias: frizzled 8, seven transmembrane spanning receptor; frizzled class receptor 8; frizzled family receptor 8; frizzled homolog 8; frizzled homolog 8 (Drosophila); frizzled-8; Fz8; Fz-8; Fzd8; hFZ8; HGNC:4046
• Gene Symbols: Fzd8
• Host Species: Rabbit
• Immunogen: Recombinant protein within Human Frizzled 8 aa 561-694.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8325
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles, store in dark
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG