Invitrogen™ G0S2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597764

Catalog No. PIPA597764

Description

G0S2 Polyclonal Antibody for IHC (P)

The G(0)-G(1) switch gene 2 (G0S2) codes for a mitochondrial protein that is important in apoptosis, lipolysis, and triacylglycerol hydrolysis. In adipocytes, G0S2 binds to adipose triglyceride lipase and decreases the breakdown of lipid droplets. In Crohn's colitis, the presence of G0S2 is increased in correlation to the amount of non-converted lipid in waste. In squamous lung cancer, mutations in the G0S2 gene are common. In breast cancer, epigenetic silencing of G0S2 occurs, and normal apoptotic regulation of aberrant cells is negatively impacted. However, when G0S2 is not epigenetically modified, it is the best mediator of the Bcl-2/Bax heterodimer, resulting in apoptosis of cancerous cells.

Specifications

• Antigen: G0S2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: G0s2
• Gene Alias: AI255151; AV006465; G0/G1 switch 2; G0/G1 switch gene 2; G0/G1 switch protein 2; G0/G1 switch regulatory protein 2; G0/G1switch 2; G0s2; G0S2-like protein; putative lymphocyte G0/G1 switch; Putative lymphocyte G0/G1 switch gene; putative lymphocyte G0/G1 switch protein 2; RP1-28O10.2
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 50486
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 3 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: P27469
• Gene Symbols: G0s2
• Immunogen: Recombinant Human G0/G1 switch protein 2 protein (1-103AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov