Invitrogen™ G6PD Monoclonal Antibody (5E12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515918

Catalog No. PIMA515918

Description

MA5-15918 targets G6PD in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples. The MA5-15918 immunogen is purified recombinant fragment of human G6PD expressed in E. Coli. . MA5-15918 detects G6PD which has a predicted molecular weight of approximately 59kDa.

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: G6PD
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: P11413
• Gene Symbols: G6PD
• Immunogen: Purified recombinant fragment of human G6PD expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 2539
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 5E12
• Conjugate: Unconjugated
• Gene: G6PD
• Gene Alias: G28A; G6PD; G6PD1; G6pd-1; G6pdx; Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase X; glucose-6-phosphate dehydrogenase; glucose-6-phosphate dehydrogenase X-linked; Gpdx
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1