Invitrogen™ G6PD Recombinant Rabbit Monoclonal Antibody (JA31-40)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA532681

Catalog No. PIMA532681

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: G6PD
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P11413
• Gene Symbols: G6PD
• Immunogen: Synthetic peptide within Human Glucose 6 Phosphate Dehydrogenase aa 460-509.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Clone: JA31-40
• Conjugate: Unconjugated
• Gene: G6PD
• Gene Alias: G28A; G6PD; G6PD1; G6pd-1; G6pdx; Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase X; glucose-6-phosphate dehydrogenase; glucose-6-phosphate dehydrogenase X-linked; Gpdx
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2539
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid