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Invitrogen™ GAB2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518705

Catalog No. PIPA518705


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Description

Description

This antibody is predicted to react with canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GAB2
Polyclonal
Unconjugated
GAB2
AI463667; D130058I17Rik; GAB2; Grb2 associated binder 2; GRB2 associated binding protein 2; GRB2-associated binder 2; GRB2-associated binding protein 2; GRB2-associated-binding protein 2; GRB3-3; Growth factor receptor bound protein 2-associated protein 2; KIAA0571; p97; PH domain-containing adaptor molecule p97; pp100
Goat
Ammonium sulfate precipitation
RUO
9846
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Q9UQC2
GAB2
Synthetic peptide sequence (QVDKEKTQALQN) corresponding to the internal amino acids of GAB2 (aa 645-657).
100 μg
Primary
Human
Antibody
IgG
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