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Invitrogen™ GAB2 Polyclonal Antibody
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Catalog No. PIPA5119921
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100 μL
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PIPA5119921 100 μL
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Catalog No. PIPA5119921 Supplier Invitrogen™ Supplier No. PA5119921
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Description

Rabbit Polyclonal Antibody

Positive Control: Hela cell lysate, mouse brain tissue lysate, rat brain tissue lysates, SHSY5Y cell lysates, rat kidney tissue, human throid gland tissue, human esophagus tissue, A549, SH-SY5Y. Subcellular Location: Cell membrane, Cytoplasm.

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GAB2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4
Gene GAB2
Gene Accession No. Q9EQH1, Q9UQC2, Q9Z1S8
Gene Alias AI463667; D130058I17Rik; GAB2; Grb2 associated binder 2; GRB2 associated binding protein 2; GRB2-associated binder 2; GRB2-associated binding protein 2; GRB2-associated-binding protein 2; GRB3-3; Growth factor receptor bound protein 2-associated protein 2; KIAA0571; p97; PH domain-containing adaptor molecule p97; pp100
Gene Symbols GAB2
Host Species Rabbit
Immunogen Recombinant protein within human GAB2 aa 450-676.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14389, 84477, 9846
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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