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GABBR1 (extracellular) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA577414

Catalog No. PIPA577414


Description

Description

Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt. Reconstitute using 50 uL deionized water.

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GABBR1 (extracellular)
Polyclonal
Unconjugated
GABBR1
GABAB, GABABR1
Rabbit
Antigen affinity chromatography
RUO
2550, 54393, 81657
-20°C
Lyophilized
Immunofluorescence, Immunohistochemistry, Western Blot
0.8 mg/mL
PBS with 1% BSA and 0.05% sodium azide; pH 7.4
Q9UBS5, Q9WV18, Q9Z0U4
Gabbr1
Peptide CRGEREVVGPKVRK, corresponding to amino acid residues 66-79 of rat GABA(B) R1
50 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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