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GABBR1 (extracellular) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA577414
Description
Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt. Reconstitute using 50 uL deionized water.
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants.
Specifications
GABBR1 (extracellular) | |
Polyclonal | |
Unconjugated | |
GABBR1 | |
GABAB, GABABR1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
2550, 54393, 81657 | |
-20°C | |
Lyophilized |
Immunofluorescence, Immunohistochemistry, Western Blot | |
0.8 mg/mL | |
PBS with 1% BSA and 0.05% sodium azide; pH 7.4 | |
Q9UBS5, Q9WV18, Q9Z0U4 | |
Gabbr1 | |
Peptide CRGEREVVGPKVRK, corresponding to amino acid residues 66-79 of rat GABA(B) R1 | |
50 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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