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Invitrogen™ GABBR2 Monoclonal Antibody (N81/2), FITC
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Catalog No. PIMA545534
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100 μg
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PIMA545534 100 μg
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Catalog No. PIMA545534 missing translation for 'mfr' Invitrogen™ missing translation for 'supplierNo' MA545534
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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45534 was sufficient for detection of GABA(B)R2 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 105kDa. No cross-reactivity against GABA(B)R1. This antibody was formerly sold as clone S81-2.

The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GABBR2
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone N81/2
Concentration 1 mg/mL
Conjugate FITC
Formulation PBS, 9.1mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4
Gene GABBR2
Gene Accession No. O75899, O88871, Q80T41
Gene Alias FLJ36928; G protein-coupled receptor 51; GABA BR; GABA-B R2 receptor; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABABR2; GABA-BR2; GABA-B-R2; Gabbr2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor 2; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; gamma-aminobutyric acid type B receptor subunit 2; gamma-aminobutyric acid type B receptor, subunit 2; gb2; Gm425; Gpr51; GPRC3B; G-protein coupled receptor 51; HG20; HRIHFB2099; MGC119386; MGC119388; MGC119389; ortholog of human G protein-coupled receptor 51 GPR51; RP23-337N2.1
Gene Symbols GABBR2
Host Species Mouse
Immunogen Fusion protein amino acids 861-912 of rat GABA(B)R2.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 242425, 83633, 9568
Target Species Human, Mouse, Rat
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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