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Tocris Bioscience™ Gabexate mesylate
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Catalog No. 179810
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50 mg
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Catalog No. Quantity
17-981-0 10 mg
17-985-0 50 mg
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Catalog No. 17-981-0 Supplier Tocris Bioscience™ Supplier No. 1798/10
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Description

Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin

Gabexate mesylate is a serine protease inhibitor; Gabexate mesylate inhibits trypsin, plasmin, plasma kallikrein and thrombin (IC50 values are 9.4, 30, 41 and 110 μM respectively). Antithrombotic in vitro and in vivo. Gabexate mesylate also inhibits LPS-induced TNF-α production, probably by inhibiting NF-κB and AP-1 activation. Gabexate mesylate attenuates allergen-induced airway inflammation and eosinophils infiltration in the lung of asthma murine model.

Chemical Identifiers

CAS 56974-61-9
Molecular Formula C17H27N3O7S

Specifications

Quantity 10 mg
Formula Weight 417.48
Purity >98%
Molecular Weight (g/mol) 417.48
Chemical Name or Material Gabexate mesylate

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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