Invitrogen™ GABPA Polyclonal Antibody

Catalog No.	Quantity
PIPA527735	100 μL

Catalog No. PIPA527735 Supplier Invitrogen™ Supplier No. PA527735

Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2. Predicted reactivity: Mouse (97%), Rat (99%), Xenopus laevis (82%), Chicken (86%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: GABPA
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.33 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene: GABPA
• Gene Accession No.: Q00422, Q06546
• Gene Alias: E4TF1-60; E4TF1A; GA binding protein transcription factor alpha subunit; GA binding protein transcription factor alpha subunit 60kDa; GA binding protein transcription factor, alpha subunit; GA binding protein transcription factor, alpha subunit 60kDa; GA repeat binding protein alpha; GA repeat binding protein, alpha; GA-binding protein alpha chain; GA-binding protein alpha-subunit; GABP subunit alpha; GABPA; GABPalpha; human nuclear respiratory factor-2 subunit alpha; NFT2; NRF2; Nrf2a; Nrf-2alpha; nuclear respiratory factor 2 alpha; nuclear respiratory factor 2 alpha subunit; nuclear respiratory factor 2 subunit alpha; RCH04A07; Transcription factor E4TF1-60
• Gene Symbols: GABPA
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GABPA. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14390, 2551, 363735
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG