Invitrogen™ GABPA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588475

Catalog No. PIPA588475

Description

Immunogen sequence: MTKREAEELI EIEIDGTEKA ECTEESIVEQ TYAPAECVSQ AIDINEPIGN LKKLLEPRLQ CSLDAHEICL QDIQLDPERS LFDQGVKTDG TVQLSVQVIS; Positive Samples: HeLa, HepG2, Rat liver; Cellular Location: Nucleus.

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: GABPA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GABPA
• Gene Alias: E4TF1-60; E4TF1A; GA binding protein transcription factor alpha subunit; GA binding protein transcription factor alpha subunit 60kDa; GA binding protein transcription factor, alpha subunit; GA binding protein transcription factor, alpha subunit 60kDa; GA repeat binding protein alpha; GA repeat binding protein, alpha; GA-binding protein alpha chain; GA-binding protein alpha-subunit; GABP subunit alpha; GABPA; GABPalpha; human nuclear respiratory factor-2 subunit alpha; NFT2; NRF2; Nrf2a; Nrf-2alpha; nuclear respiratory factor 2 alpha; nuclear respiratory factor 2 alpha subunit; nuclear respiratory factor 2 subunit alpha; RCH04A07; Transcription factor E4TF1-60
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2551, 363735
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q06546
• Gene Symbols: GABPA
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GABPA (NP_0020312).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov