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Invitrogen™ GABRA2 Polyclonal Antibody
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Catalog No. PIPA14713
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100 μL
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PIPA14713 100 μL
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Catalog No. PIPA14713 Supplier Invitrogen™ Supplier No. PA14713
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Description

Rabbit Polyclonal Antibody

PA1-4713 is specific for the ~51k alpha-2-subunit of the GABAA receptor. In Western blot, labeling is absent in alpha-2-subunit knockout animals. This antibody is predicted to react with bovine, canine, human, non-human primate and Zebrafish based on 100% sequence homology.

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GABRA2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene GABRA2
Gene Accession No. P23576, P26048
Gene Alias C630048P16Rik; FLJ97076; GABA(A) receptor; GABA(A) receptor subunit alpha-2; GABA(A) receptor, alpha 2; GABAARalpha2; Gabra2; Gabra-2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2; gamma-aminobutyric acid A receptor alpha 2; gamma-aminobutyric acid receptor A2 subunit; gamma-aminobutyric acid receptor subunit alpha-2; gamma-aminobutyric acid type A receptor alpha2 subunit
Gene Symbols GABRA2
Host Species Rabbit
Immunogen Fusion protein from the cytoplasmic loop of the alpha 2 subunit of rat GABRA2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14395, 289606
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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