Invitrogen™ GABRA2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA14713

Catalog No. PIPA14713

Description

PA1-4713 is specific for the ~51k alpha-2-subunit of the GABAA receptor. In Western blot, labeling is absent in alpha-2-subunit knockout animals. This antibody is predicted to react with bovine, canine, human, non-human primate and Zebrafish based on 100% sequence homology.

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: GABRA2
• Classification: Polyclonal
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: P23576, P26048
• Gene Symbols: GABRA2
• Immunogen: Fusion protein from the cytoplasmic loop of the alpha 2 subunit of rat GABRA2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Gene: GABRA2
• Gene Alias: C630048P16Rik; FLJ97076; GABA(A) receptor; GABA(A) receptor subunit alpha-2; GABA(A) receptor, alpha 2; GABAARalpha2; Gabra2; Gabra-2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2; gamma-aminobutyric acid A receptor alpha 2; gamma-aminobutyric acid receptor A2 subunit; gamma-aminobutyric acid receptor subunit alpha-2; gamma-aminobutyric acid type A receptor alpha2 subunit
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14395, 289606
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov