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GABRA4 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501567595
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50-156-7595 10 μL
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Catalog No. 50-156-7595 Supplier Bethyl Laboratories, Inc Supplier No. A304386AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Gamma-aminobutyric acid is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1. Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

Specifications

Antigen GABRA4
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene GABRA4
Gene Accession No. P48169
Gene Alias GABRA4; gamma-aminobutyric acid (GABA) A receptor, alpha 4; gamma-aminobutyric acid A receptor, alpha 4
Gene Symbols GABRA4
Host Species Rabbit
Immunogen Between 425 and 475
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2557
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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