Invitrogen™ GABRA5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597293

Catalog No. PIPA597293

Description

Immunogen sequence: QMPTSSVKDE TNDNITIFTR ILDGLLDGYD NRLRPGLGER ITQVRTDIYV TSFGPVSDTE MEYTIDVFFR QSWKDERLRF KGPMQRLPLN NLLASKIWTP DTFFHNGKKS IAHNMTTPNK LLRLEDDGTL LYTMRLTISA ECPMQLEDFP MDAHACPLKF GSYAYPNSEV VYVWTNGSTK SVVVAEDGSR LNQYHLMGQT VGTENISTST GEYTIMTAHF HLKRKIGY; Positive Samples: Mouse brain, Mouse skeletal muscle, Mouse pancreas, Rat brain, Rat skeletal muscle; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse.

GABRA5 is a part of GABA, a major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.

Specifications

• Antigen: GABRA5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GABRA5
• Gene Alias: A230018I05Rik; GABA(A) receptor; GABA(A) receptor subunit alpha-5; GABAA receptor alpha5 subunit; GABA-A receptor alpha-5 subunit; GABRA5; Gabra-5; gamma-aminobutyric acid; gamma-aminobutyric acid A receptor, alpha 5; gamma-aminobutyric acid (GABA) A receptor, alpha 5; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5; gamma-aminobutyric acid A receptor, alpha 5; gamma-aminobutyric acid receptor subunit alpha-5; gamma-aminobutyric acid type A receptor alpha5 subunit; ligand-gated ion channel subunit
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 110886, 29707
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.63 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P19969, Q8BHJ7
• Gene Symbols: GABRA5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 32-259 of human GABRA5 (NP_0008011).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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