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Invitrogen™ GABRA5 Polyclonal Antibody
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Catalog No. PIPA597293
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100 μL
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PIPA597293 100 μL
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Catalog No. PIPA597293 Supplier Invitrogen™ Supplier No. PA597293
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QMPTSSVKDE TNDNITIFTR ILDGLLDGYD NRLRPGLGER ITQVRTDIYV TSFGPVSDTE MEYTIDVFFR QSWKDERLRF KGPMQRLPLN NLLASKIWTP DTFFHNGKKS IAHNMTTPNK LLRLEDDGTL LYTMRLTISA ECPMQLEDFP MDAHACPLKF GSYAYPNSEV VYVWTNGSTK SVVVAEDGSR LNQYHLMGQT VGTENISTST GEYTIMTAHF HLKRKIGY; Positive Samples: Mouse brain, Mouse skeletal muscle, Mouse pancreas, Rat brain, Rat skeletal muscle; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse.

GABRA5 is a part of GABA, a major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GABRA5
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.63 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GABRA5
Gene Accession No. P19969, Q8BHJ7
Gene Alias A230018I05Rik; GABA(A) receptor; GABA(A) receptor subunit alpha-5; GABAA receptor alpha5 subunit; GABA-A receptor alpha-5 subunit; GABRA5; Gabra-5; gamma-aminobutyric acid; gamma-aminobutyric acid A receptor, alpha 5; gamma-aminobutyric acid (GABA) A receptor, alpha 5; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5; gamma-aminobutyric acid A receptor, alpha 5; gamma-aminobutyric acid receptor subunit alpha-5; gamma-aminobutyric acid type A receptor alpha5 subunit; ligand-gated ion channel subunit
Gene Symbols GABRA5
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 32-259 of human GABRA5 (NP_0008011).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110886, 29707
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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