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GABRB2/GABA A Receptor beta 2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981916
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50-198-1916 100 μL
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Catalog No. 50-198-1916 Supplier Bioss Supplier No. BS12065R
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Rabbit Polyclonal Antibody

GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA Rρ1 and GABAA Rρ2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

Specifications

Antigen GABRB2/GABA A Receptor beta 2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene GABRB2
Gene Accession No. P47870
Gene Alias AI834970; C030002O17Rik; C030021G16Rik; GABA(A) receptor subunit beta-2; GABAARbeta2; Gabrab2; GABRB2; Gabrb-2; gamma-aminobutyric acid (GABA) A receptor, beta 2; gamma-aminobutyric acid (GABA) A receptor, subunit beta 2; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 2; gamma-aminobutyric acid A receptor beta 2; gamma-aminobutyric acid A receptor, subunit beta 2; Gamma-aminobutyric acid receptor beta 2; gamma-aminobutyric acid receptor beta-2 subunit; Gamma-aminobutyric acid receptor subunit beta-2; gamma-aminobutyric acid receptor, subunit beta 2; gamma-aminobutyric acid type A receptor beta2 subunit; GARB2; MGC119386; MGC119388; MGC119389
Gene Symbols GABRB2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human GABRB2/GABA A Receptor beta 2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2561
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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