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Invitrogen™ GABRB2 Recombinant Rabbit Monoclonal Antibody (6G9O8)
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Catalog No. PIMA535130
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100 μL
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PIMA535130 100 μL
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Catalog No. PIMA535130 Supplier Invitrogen™ Supplier No. MA535130
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: PYVKAIDMYL MGCFVFVFMA LLEYALVNYI FFGRGPQRQK KAAEKAASAN NEKMRLDVNK IFYKDIKQNG TQYRSLWDPT GNLSPTRRTT NYDFSLYTMD P.

GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA Rρ1 and GABAA Rρ2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GABRB2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 6G9O8
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GABRB2
Gene Accession No. P47870, P63137, P63138
Gene Alias AI834970; C030002O17Rik; C030021G16Rik; GABA(A) receptor subunit beta-2; GABAARbeta2; Gabrab2; GABRB2; Gabrb-2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, beta 2; gamma-aminobutyric acid (GABA) A receptor, subunit beta 2; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 2; gamma-aminobutyric acid A receptor beta 2; gamma-aminobutyric acid A receptor, subunit beta 2; Gamma-aminobutyric acid receptor beta 2; gamma-aminobutyric acid receptor beta-2 subunit; gamma-aminobutyric acid receptor subunit beta-2; gamma-aminobutyric acid receptor, subunit beta 2; gamma-aminobutyric acid type A receptor beta2 subunit; GARB2; MGC119386; MGC119388; MGC119389
Gene Symbols GABRB2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 300-400 of human GABA A Receptor beta 2 (GABRB2) (GABRB2) (P47870).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14401, 25451, 2561
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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