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Invitrogen™ GABRB3 Polyclonal Antibody
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Catalog No. PIPA519060
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100 μg
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Catalog No. Quantity
PIPA519060 100 μg
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Catalog No. PIPA519060 Supplier Invitrogen™ Supplier No. PA519060
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000. Preliminary analysis showed no signal in Western Blot.

Gamma-amino butyric acid (GAMA) is a strong inhibitor of neuron transmission and is found throughout the central nervous system. GABA is formed by the decarboxylation of glutamate, resulting in the formation of one of two distinct types; GABA-A or GABA-B.The binding of GABA to GABA-A receptors results in the increase transportation of chlorine ions into the neuron. This influx results in signal transmission repression. Studies have shown that if cell to cell signaling goes unchecked due to a lack of GABA, a system overload can resulting in blackouts, rapid body contractions, seizures and epilepsy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GABRB3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene GABRB3
Gene Accession No. P28472
Gene Alias A230092K12Rik; AW049585; beta3; cleft palate 1; Cp1; ECA5; GABA(A) receptor subunit beta-3; GABAA receptor beta-3 subunit; GABA-alpha receptor beta-2 subunit; GABR B3; Gabrb3; Gabrb-3; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, beta 3; gamma-aminobutyric acid (GABA) A receptor, subunit beta 3; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 3; gamma-aminobutyric acid A receptor beta 3; Gamma-aminobutyric acid receptor beta 3; gamma-aminobutyric acid receptor subunit beta-3; gamma-aminobutyric acid receptor, subunit beta 3; gamma-aminobutyric acid type A receptor beta3 subunit; gamma-aminobutyric acid type A receptor subunit beta3; LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit beta-3; MGC9051; testis gamma-aminobutyric acid receptor subunit beta 3
Gene Symbols GABRB3
Host Species Goat
Immunogen Synthetic peptide sequence (EKTAKAKNDRSK) corresponding to the internal amino acids of GABRB3 (aa 344-356).
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2562
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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