Invitrogen™ GABRB3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579292

Catalog No. PIPA579292

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Brain Tissue, Mouse Brain Tissue.

Gamma-amino butyric acid (GAMA) is a strong inhibitor of neuron transmission and is found throughout the central nervous system. GABA is formed by the decarboxylation of glutamate, resulting in the formation of one of two distinct types; GABA-A or GABA-B.The binding of GABA to GABA-A receptors results in the increase transportation of chlorine ions into the neuron. This influx results in signal transmission repression. Studies have shown that if cell to cell signaling goes unchecked due to a lack of GABA, a system overload can resulting in blackouts, rapid body contractions, seizures and epilepsy.

Specifications

• Antigen: GABRB3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GABRB3
• Gene Alias: A230092K12Rik; AW049585; beta3; cleft palate 1; Cp1; ECA5; GABA(A) receptor subunit beta-3; GABAA receptor beta-3 subunit; GABA-alpha receptor beta-2 subunit; GABR B3; Gabrb3; Gabrb-3; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, beta 3; gamma-aminobutyric acid (GABA) A receptor, subunit beta 3; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 3; gamma-aminobutyric acid A receptor beta 3; Gamma-aminobutyric acid receptor beta 3; gamma-aminobutyric acid receptor subunit beta-3; gamma-aminobutyric acid receptor, subunit beta 3; gamma-aminobutyric acid type A receptor beta3 subunit; gamma-aminobutyric acid type A receptor subunit beta3; LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit beta-3; MGC9051; testis gamma-aminobutyric acid receptor subunit beta 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14402, 24922, 2562
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: P28472, P63079, P63080
• Gene Symbols: GABRB3
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human GABRB3 (344-375aa EKTAKAKNDRSKSESNRVDAHGNILLTSLEVH).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG