Invitrogen™ GABRG1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557340

Catalog No. PIPA557340

Description

Immunogen sequence: RGVRLVFLLL TLHLGNCVDK ADDEDDEDLT VNKTWVLAPK IHEGDITQIL Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 94%.

Gabrg1 encodes a protein that belongs to the ligand-gated ionic channel family. Gabrg1 is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. The Gabrg1 gene is clustered with three other family members on chromosome 4. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, are responsible for mediating the inhibitory effects of GABA. Structurally, Gabrg1 are pentameric proteins, consisting of five subunits belonging to different families. Diseases associated with GABRG1 include Alcohol Dependence.

Specifications

• Antigen: GABRG1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gabrg1
• Gene Alias: GABA(A) receptor subunit gamma-1; GABA(A) receptor, gamma; GabaA; GabaA/BZ; GABAAR gamma1; Gabeg1; Gabrg1; gamma-1 polypeptide; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 1; gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 1; gamma-aminobutyric acid A receptor, gamma 1; gamma-aminobutyric acid receptor subunit gamma-1; gamma-aminobutyric acid type A receptor gamma1 subunit
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2565
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8N1C3
• Gene Symbols: Gabrg1
• Immunogen: Recombinant protein corresponding to Human GABRG1. Recombinant protein control fragment (Product #RP-96574).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov