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Invitrogen™ GABRG1 Polyclonal Antibody
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Catalog No. PIPA5119791
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100 μL
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PIPA5119791 100 μL
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Catalog No. PIPA5119791 Supplier Invitrogen™ Supplier No. PA5119791
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Description

Rabbit Polyclonal Antibody

Positive Control: LOVO cell lysate, rat brain tissue lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, rat brian tissue, mouse brian tissue. Subcellular Location: Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse.

Gabrg1 encodes a protein that belongs to the ligand-gated ionic channel family. Gabrg1 is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. The Gabrg1 gene is clustered with three other family members on chromosome 4. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, are responsible for mediating the inhibitory effects of GABA. Structurally, Gabrg1 are pentameric proteins, consisting of five subunits belonging to different families. Diseases associated with GABRG1 include Alcohol Dependence.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GABRG1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Gabrg1
Gene Accession No. P23574, Q8N1C3, Q9R0Y8
Gene Alias GABA(A) receptor subunit gamma-1; GABA(A) receptor, gamma; GabaA; GabaA/BZ; GABAAR gamma1; Gabeg1; Gabrg1; gamma-1 polypeptide; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 1; gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 1; gamma-aminobutyric acid A receptor, gamma 1; gamma-aminobutyric acid receptor subunit gamma-1; gamma-aminobutyric acid type A receptor gamma1 subunit
Gene Symbols Gabrg1
Host Species Rabbit
Immunogen Synthetic peptide within human GABA A Receptor gamma 1 aa 350-406.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140674, 14405, 2565
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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