Invitrogen™ GABRG1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119791

Catalog No. PIPA5119791

Description

Positive Control: LOVO cell lysate, rat brain tissue lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, rat brian tissue, mouse brian tissue. Subcellular Location: Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse.

Gabrg1 encodes a protein that belongs to the ligand-gated ionic channel family. Gabrg1 is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. The Gabrg1 gene is clustered with three other family members on chromosome 4. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, are responsible for mediating the inhibitory effects of GABA. Structurally, Gabrg1 are pentameric proteins, consisting of five subunits belonging to different families. Diseases associated with GABRG1 include Alcohol Dependence.

Specifications

• Antigen: GABRG1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gabrg1
• Gene Alias: GABA(A) receptor subunit gamma-1; GABA(A) receptor, gamma; GabaA; GabaA/BZ; GABAAR gamma1; Gabeg1; Gabrg1; gamma-1 polypeptide; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 1; gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 1; gamma-aminobutyric acid A receptor, gamma 1; gamma-aminobutyric acid receptor subunit gamma-1; gamma-aminobutyric acid type A receptor gamma1 subunit
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 140674, 14405, 2565
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P23574, Q8N1C3, Q9R0Y8
• Gene Symbols: Gabrg1
• Immunogen: Synthetic peptide within human GABA A Receptor gamma 1 aa 350-406.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG