Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
GAD1 Mouse anti-Human, Clone: OTI5D8, liquid, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene TA500330

Description
GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA ( gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 will transiently activate to assist in GABA production. The loss of GAD-65 is detrimental and can impair GABA neurotransmission, however the loss of GAD-67 is lethal. Due to alternative splicing, two isoforms exist for GAD-67: the predomit GAD-67 form and the minor GAD-25 form.Specifications
GAD1 | |
Monoclonal | |
0.5 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
Q99259 | |
GAD1 | |
Full-length protein expressed in 293T cell transfected with human GAD1 expression vector | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
OTI5D8 | |
Unconjugated | |
GAD1 | |
CPSQ1, GAD, SCP | |
Mouse | |
Affinity Chromatography | |
RUO | |
2571 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction