Invitrogen™ GADD34 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1139

Catalog No. PIPA1139

Description

Western blot analysis of PA1-139 detects an ~73 kDa protein in HeLa cells. PA1-139 shows specificity to GADD34 and can be blocked by incubating with an abundance of the immunizing peptide.

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

Specifications

• Antigen: GADD34
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP1R15A
• Gene Alias: 9630030H21; Gadd34; growth arrest and DNA damage-inducible protein GADD34; growth arrest and DNA-damage-inducible 34; Myd116; myeloid differentiation primary response gene 116; myeloid differentiation primary response protein MyD116; Myeloid differentiation primary response protein MyD116 homolog; Peg3; PEG-3; PPP1R15A; PR15A; Progression elevated gene 3 protein; protein phosphatase 1 regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A; protein phosphatase 1, regulatory subunit 15A; RGD1624209
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17872, 23645
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: O75807, P17564
• Gene Symbols: PPP1R15A
• Immunogen: A synthetic peptide corresponding to amino acids C R(595) I T Q A Q E E L S P C L T P A A R(612) from human GADD34.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov