GADD45A Mouse anti-Human, Clone: OTI2B7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF507380

Catalog No. 50-166-4761

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

GADD45 alpha, beta and gamma are an evolutionarily conserved, homologous family of nuclear proteins that function as stress sensors for cellular physiological and environmental damage. GADD45 proteins are required for the activation of the G2/M checkpoint induced by UV radiation or alkylating agents. GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase. GADD45 forms a complex with p21 and Cdc2, and may serve as core for interaction with other cell cycle regulators.

Specifications

• Antigen: GADD45A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: GADD45A
• Gene Alias: DDIT1, GADD45
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1647
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI2B7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P24522
• Gene Symbols: GADD45A
• Immunogen: Full length human recombit protein of human GADD45A produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1