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Invitrogen™ GADD45A Polyclonal Antibody
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Catalog No. PIPA512383
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400 μL
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Catalog No. Quantity
PIPA512383 400 μL
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Catalog No. PIPA512383 Supplier Invitrogen™ Supplier No. PA512383
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine based on sequence homology.

GADD45 alpha, beta and gamma are an evolutionarily conserved, homologous family of nuclear proteins that function as stress sensors for cellular physiological and environmental damage. GADD45 proteins are required for the activation of the G2/M checkpoint induced by UV radiation or alkylating agents. GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase. GADD45 forms a complex with p21 and Cdc2, and may serve as core for interaction with other cell cycle regulators.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GADD45A
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene GADD45A
Gene Accession No. P24522
Gene Alias AA545191; DDIT 1; DDIT1; DDIT-1; DNA damage-inducible transcript 1 protein; DNA damage-inducible transcript-1; DNA-damage inducible transcript 1; DNA-damage-inducible transcript 1; GADD45; GADD45A; Gadd45alpha; growth arrest and DNA damage inducible alpha; growth arrest and DNA damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible 45 alpha; growth arrest and DNA-damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible, alpha
Gene Symbols GADD45A
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GADD45A.
Purification Method Ammonium sulfate precipitation, Size-exclusion - Dialysis
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1647
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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