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Invitrogen™ GAK Polyclonal Antibody
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Catalog No. PIPA555628
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100 μL
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PIPA555628 100 μL
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Catalog No. PIPA555628 Supplier Invitrogen™ Supplier No. PA555628
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VLAEGGFAFV YEAQDVGSGR EYALKRLLSN EEEKNRAIIQ EVCFMKKLSG HPNIVQFCSA ASIGKEESDT GQAEFLLLTE LCKGQLVE Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

GAK serine/threonine kinase or Cyclin-G-associated kinase was originally identified as a protein that is associated with cyclin G. However, neither CDK5 nor GAK kinase activity is activated by cyclin G nor does GAK affect CDK5 kinase activity. GAK seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GAK
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GAK
Gene Accession No. O14976
Gene Alias auxilin-2; cyclin G associated kinase; cyclin G-associated kinase; cyclin-G-associated kinase; D130045N16Rik; DNAJ26; DNAJC26; GAK
Gene Symbols GAK
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GAK. Recombinant protein control fragment (Product #RP-95240).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2580
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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