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Invitrogen™ GAL4 Monoclonal Antibody (2GV-3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA3031

Catalog No. MA3031


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Description

Description

MA3-031 recognizes Gal4 DNA Binding Domain corresponding to amino acids 1-147 of the GAL4 DNA binding region.

GAL4 is a transcriptional activator which activates genes necessary for galactose catabolism. The DNA binding domain of GAL4 is contained in the first 74 amino acids and contains a zinc finger sequence motif. However, amino acids 1-147 have been shown to bind to DNA in vitro. While GAL4 (1-74) bind DNA specifically, it is with a lower affinity than the GAL4 (1-147). GAL4 (1-147) binds to a specific 17 base pair nucleotide sequence, but alone is insufficient to activate transcription. Either of the two acidic activating regions, activating region I (amino acids 148-238) or activating region II (amino acids 768-881), must be joined to activate transcription.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GAL4
Monoclonal
Conc. Not Determined
Ascites with 0.05% sodium azide
P04386
GAL4
Gal4 DNA Binding Domain aa1-147.
RUO
855828
-20°C
Liquid
Western Blot, Immunocytochemistry
2GV-3
Unconjugated
GAL4
antigen NY-CO-27; GAL4; Gal-4; GAL81; galactose-responsive transcription factor GAL4; galectin 4; galectin-4; L-36 lactose-binding protein; L36LBP; Lactose-binding lectin 4; lectin, galactoside binding soluble 4; lectin, galactoside-binding, soluble, 4; LGALS4; Regulatory protein GAL4; YPL248C
Mouse
50 μL
Primary
Yeast
Antibody
IgG κ
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