Invitrogen™ GALC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109753

Catalog No. PIPA5109753

Description

Immunogen sequence: GGAYVLDDSD GLGREFDGIG AVSGGGATSR LLVNYPEPYR SQILDYLFKP NFGASLHILK VEIGGDGQTT DGTEPSHMHY ALDENYFRGY EWWLMKEAKK RNPNITLIGL PWSFPGWLGK GFDWPYVNLQ LTAYYVVTWI VGAKRYHDLD IDYIGIWNER SYNANYIKIL RKMLNYQGLQ RVKIIASDNL WESISASMLL DAELFKVVDV IGAHYPGTHS AKDAKLTGKK LWSSEDFSTL NSDMGAGCWG RILNQNYING Y.

This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: GALC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Galc
• Gene Alias: 2310068B06Rik; 3.2.1.46; A930008M05Rik; AW212969; AW413532; beta-galactosidase; casein kinase 2, beta polypeptide pseudogene; Gacy; Galactocerebrosidase; galactocerebroside beta-galactosidase; Galactosylceramidase; galactosylceramidase (Krabbe disease); galactosylceramide beta-galactosidase; galactosylceraminidase; GALC; GALCERase; testis tissue sperm-binding protein Li 88E; testis tissue sperm-binding protein Li 89A; twi; twitcher
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14420, 2581, 314360
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P54803, P54818
• Gene Symbols: Galc
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GALC (NP_000144.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG