GALE/Galactowaldenase Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2753	100 μL

Catalog No. 50-198-2753 Supplier Bioss Supplier No. BS13265R

Description

Rabbit Polyclonal Antibody

This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild (′peripheral′ form) to severe (′generalized′ form). Multiple alternatively spliced transcripts encoding the same protein have been identified.

Specifications

• Antigen: GALE/Galactowaldenase
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: GALE
• Gene Accession No.: Q14376
• Gene Alias: 2310002A12Rik; AI323962; BOS_2427; galactose-4-epimerase, UDP; galactose-4-epimerase, UDP-; Galactowaldenase; Gale; LOC100345092; SDR1E1; short chain dehydrogenase/reductase family 1E, member 1; UDP galactose-4′-epimerase; UDP-galactosamine 4-epimerase; UDP-galactose 4-epimerase; UDP-galactose-4-epimerase; UDP-GalNAc 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-glucose 4-epimerase; UDP-N-acetylgalactosamine 4-epimerase; UDP-N-acetylglucosamine 4-epimerase
• Gene Symbols: GALE
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human GALE/Galactowaldenase.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2582
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG