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GALE Mouse anti-Canine, Human, Rat, Clone: OTI1C4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF502146

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild (′peripheral′ form) to severe (′generalized′ form). Multiple alternatively spliced transcripts encoding the same protein have been identified.Specifications
GALE | |
Monoclonal | |
Unconjugated | |
GALE | |
SDR1E1 | |
Mouse | |
Affinity Chromatography | |
RUO | |
100855555, 114860, 2582 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI1C4 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P18645, Q14376 | |
GALE | |
Full length human recombit protein of human GALE produced in HEK293T cell. | |
100 μg | |
Primary | |
Canine, Human, Rat | |
Antibody | |
IgG1 |
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