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  6. Invitrogen™ Galectin 12 Polyclonal Antibody, Invitrogen™

Invitrogen™ Galectin 12 Polyclonal Antibody, Invitrogen™
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Catalog No. FEPA5145433
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200 μL
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FEPA5145433 200 μL
FEPA5145434 20 μL
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Catalog No. FEPA5145433 Supplier Invitrogen™ Supplier No. PA5145433
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Description

Rabbit Polyclonal Antibody

Galectin-12, also designated galectin-related inhibitor of proliferation 1 in mouse, is a 314 amino acid protein encoded by the human gene LGALS12. Galectin-12 is a member of the galectin family consisting of b-galactoside-binding proteins with conserved carbohydrate recognition domains. Galectin-12 binds lactose and may participate in the apoptosis of adipocytes. This protein is preferentially expressed in peripheral blood leukocytes and adipocytes. Galectin-12 is induced by cell cycle block at the G1 phase and causes G1 arrest when overexpressed. The galectin-12 gene is expressed in mouse preadipo-cytes and is upregulated when preadipocytes undergo cell cycle arrest, concomitant with acquisition of the competence to undergo differentiation in response to adipogenic hormone stimulation. Galectin-12 is an adipocyte-expressed protein which is downregulated by various insulin resistance-inducing hormones. As a result, galectin-12 may play a role in the pathogenesis of insulin resistance.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Galectin 12
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene LGALS12
Gene Alias AW987437; GAL12; gal-12; galectin 12; galectin-12; Galectin-related inhibitor of proliferation; galectin-related inhibitor of proliferation 1; GRIP1; lectin, galactose binding, soluble 12; lectin, galactoside binding soluble 12; lectin, galactoside-binding, soluble, 12; LGALS12; testicular secretory protein Li 26
Gene Symbols LGALS12
Host Species Rabbit
Immunogen Recombinant Pig GAL12 protein, Met1-Tyr314 (Accession #B7U2G9).
Purification Method Antigen affinity chromatography, Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100217395
Target Species Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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