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Invitrogen™ Galectin 14 Monoclonal Antibody (511124)
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Catalog No. PIMA524223
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100 μg
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PIMA524223 100 μg
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Catalog No. PIMA524223 Supplier Invitrogen™ Supplier No. MA524223
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Mouse Monoclonal Antibody

In direct ELISAs, no cross-reactivity with recombinant human Galectin-1, -2, -3, -4, -7, -8, -10, or recombinant mouse Galectin-9 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Galectin-14 is a member of the galectin family of proteins, which are characterized by their affinity for beta-galactoside sugars and involvement in various biological processes including cell-cell adhesion, immune response modulation, and apoptosis. The gene encoding Galectin-14, LGALS14, is located on chromosome 19q13.2. Galectin-14 is predominantly expressed in eosinophils and has been identified to play a role in allergic response and inflammation. It is known to participate in the modulation of immune responses, particularly asthma and other allergic conditions, by interacting with glycoproteins on cell surfaces. The expression of Galectin-14 is elevated during allergic reactions and this molecule is considered a potential biomarker for eosinophilic activity in such conditions. There is ongoing research into the exact mechanisms of Galectin-14 in immune response modulation, which might provide insights into novel therapeutic approaches for managing allergic diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Galectin 14
Applications Western Blot
Classification Monoclonal
Clone 511124
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene LGALS14
Gene Accession No. Q8TCE9
Gene Alias Charcot-Leyden crystal protein 2; CLC2; gal-14; galectin 14; galectin-14; lectin, galactoside binding soluble 14; lectin, galactoside-binding, soluble, 14; LGALS14; MGC22235; Placental protein 13-like; placental protein 13-like protein; PPL13
Gene Symbols LGALS14
Host Species Mouse
Immunogen E. coli-derived recombinant human Galectin-14 Met1-Asp139.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56891
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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