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Invitrogen™ GALNT4 Polyclonal Antibody
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Catalog No. PIPA567407
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100 μL
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PIPA567407 100 μL
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Catalog No. PIPA567407 Supplier Invitrogen™ Supplier No. PA567407
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Rabbit Polyclonal Antibody

Immunogen sequence: IRFNSVTELCA EVPEQKNYVG MQNCPKDGFP VPANIIWHFK EDGTIFHPHS GLCLSAYRTP EGRPDVQMRT CDA Highest antigen sequence identity to the following orthologs - mouse 86%, rat 38%.

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GALNT4
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GALNT4
Gene Accession No. Q8N4A0
Gene Alias AV011803; GALNACT4; GalNAc-T4; Galnt4; Polypeptide GalNAc transferase 4; polypeptide GalNAc transferase-T4; polypeptide N-acetylgalactosaminyltransferase 4; pp-GaNTase 4; ppGaNTase-T4; protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
Gene Symbols GALNT4
Host Species Rabbit
Immunogen Recombinant Human GALNT4. Recombinant protein control fragment (Product #RP-105670).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8693
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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