Invitrogen™ GALNT4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567407

Catalog No. PIPA567407

Description

Immunogen sequence: IRFNSVTELCA EVPEQKNYVG MQNCPKDGFP VPANIIWHFK EDGTIFHPHS GLCLSAYRTP EGRPDVQMRT CDA Highest antigen sequence identity to the following orthologs - mouse 86%, rat 38%.

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon.

Specifications

• Antigen: GALNT4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GALNT4
• Gene Alias: AV011803; GALNACT4; GalNAc-T4; Galnt4; Polypeptide GalNAc transferase 4; polypeptide GalNAc transferase-T4; polypeptide N-acetylgalactosaminyltransferase 4; pp-GaNTase 4; ppGaNTase-T4; protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8693
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8N4A0
• Gene Symbols: GALNT4
• Immunogen: Recombinant Human GALNT4. Recombinant protein control fragment (Product #RP-105670).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG