Invitrogen™ GALNT6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552852

Catalog No. PIPA552852

Description

Immunogen sequence: LIMYSCHGLG GNQYFEYTTQ RDLRHNIAKQ LCLHVSKGAL GLGSCHFTGK NSQVPKDEEW ELAQDQLIRN SGSGTCLTSQ DKKPAMAPCN PSDPHQLWLF V Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 83%.

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.

Specifications

• Antigen: GALNT6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GALNT6
• Gene Alias: 4632410F13; AW047994; fc23d02; fc56f12; GalNAc transferase 6; GalNAcT6; galNAc-T6; GALNT6; N-acetylgalactosaminyltransferase T-6; polypeptide GalNAc transferase 6; Polypeptide N-acetylgalactosaminyltransferase 6; pp-GaNTase; pp-GaNTase 6; protein-UDP acetylgalactosaminyltransferase 6; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6); wu:fc23d02; wu:fc56f12; zgc:77836
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11226
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NCL4
• Gene Symbols: GALNT6
• Immunogen: Recombinant protein corresponding to Human GALNT6. Recombinant protein control fragment (Product #RP-90274).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov