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Invitrogen™ GALNT6 Polyclonal Antibody
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Catalog No. PIPA590082
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100 μL
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PIPA590082 100 μL
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Catalog No. PIPA590082 Supplier Invitrogen™ Supplier No. PA590082
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DVSSREEATE KPWLKSLVSR KDHVLDLMLE AMNNLRDSMP KLQIRAPEAQ QTLFSINQSC LPGFYTPAEL KPFWERPPQD PNAPGADGKA FQKSKWTPLE TQEKEEGYKK H; Positive Samples: U-87MG, BxPC-3; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein.

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GALNT6
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.93 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene GALNT6
Gene Accession No. Q8NCL4
Gene Alias 4632410F13; AW047994; fc23d02; fc56f12; GalNAc transferase 6; GalNAcT6; galNAc-T6; GALNT6; N-acetylgalactosaminyltransferase T-6; polypeptide GalNAc transferase 6; Polypeptide N-acetylgalactosaminyltransferase 6; pp-GaNTase; pp-GaNTase 6; protein-UDP acetylgalactosaminyltransferase 6; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6); wu:fc23d02; wu:fc56f12; zgc:77836
Gene Symbols GALNT6
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 30-140 of human GALNT6 (NP_0091412).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11226
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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