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Invitrogen™ gamma Actin Polyclonal Antibody
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Catalog No. PIPA513467
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400 μL
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PIPA513467 400 μL
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Catalog No. PIPA513467 Supplier Invitrogen™ Supplier No. PA513467
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, chicken, canine, equine, hamster, mouse, porcine, non-human primate, rat, rabbit and Xenopus, yeast and zebrafish based on sequence homology.

Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen gamma Actin
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene ACTG1
Gene Accession No. P63261
Gene Alias ACT; ACTG; Actg1; actin; actin gamma; actin gamma 1; actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; Actin, cytoplasmic type 5; actin, cytoplasmic, type 5; actin, gamma 1; actin, gamma 1 propeptide; actin, gamma, cytoplasmic 1; Actl; AL023024; beta actin; beta-actin FE-3; BRWS2; cytoplasmic 2; cytoplasmic ACTG1; cytoplasmic type 5; cytoskeletal gamma-actin; cytoskeleton actin; deafness, autosomal dominant 20; deafness, autosomal dominant 26; DFNA20; DFNA26; E51; epididymis luminal protein 176; gamma 1 propeptide; gamma actin; gamma-actin; HEL-176; type 5
Gene Symbols ACTG1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 188-215 amino acids from the central region of human ACTG1.
Purification Method Ammonium sulfate precipitation, Size-exclusion - Dialysis
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 71
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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