Invitrogen™ GANAB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589484

Catalog No. PIPA589484

Description

Immunogen sequence: MTRFRIDELE PRRPRYRVPD VLVADPPIAR LSVSGRDENS VELTMAEGPY KIILTARPFR LDLLEDRSLL LSVNARGLLE FEHQRAPRVS QGSKDPAEGD GAQPEETPRD GDKPEETQGK AEKDEPGAWE ETFKTHSDSK PYGPMSVGLD FSLPGMEHVY GIPEHADNLR LKVTEGGEPY RLYNLDVFQY ELYNPMALYG SVPVLLAHNP HRDLGIFWLN AAETWVDISS NTAGKTLFGK MMDYLQGSGE TPQTDVRWMS; Positive Samples: U-87MG, Raji, HepG2, HeLa, Mouse brain, Mouse liver, Rat brain; Cellular Location: Endoplasmic reticulum, Golgi apparatus, Melanosome.

This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.

Specifications

• Antigen: GANAB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ganab
• Gene Alias: alpha glucosidase 2 alpha neutral subunit; alpha-glucosidase 2; AU042638; carbohydrate processing enzyme of the endoplasmic reticulum; G2an; GANAB; GIIA; glucosidase II alpha subunit; glucosidase II alpha-subunit; glucosidase II subunit alpha; glucosidase, alpha; neutral AB; GLUII; KIAA0088; mKIAA0088; neutral AB; neutral alpha-glucosidase AB
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14376, 23193, 293721
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.48 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q14697, Q8BHN3
• Gene Symbols: Ganab
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_0012651231).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG